• HF is associated with the down regulation of

  2019-05-10

  

  HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th

• br Case report The patient then achieved disease

  2019-05-09

  

  Case report The patient then achieved disease-free status as noted in a series of routine image studies during regular follow-up at our oncology clinic. In November 2011, she presented due to hematuria for several days. Diagnostic cystoscopy showed a mass lesion on the urinary bladder. Whole body

• Because of high suspicion of

  2019-05-09

  

  Because of high suspicion of malignancy, we chose endoscopic ultrasound (EUS) instead of MRI of the pancreas to detect the organic lesion that caused the distal CBD stricture because initial abdominal CT did not show any suspicious lesion in the pancreas. In addition, tissue sample could be obtained

• The following is the Supplementary material related to this

  2019-05-09

  

  The following is the Supplementary material related to this article Video 1, Video 2, Video 3. Discussion In the electrophysiology setting, increased pericardial effusion or tamponade risk is associated with left-sided arrhythmia ablations, biventricular pacemaker placements, and implantable car

• br Conflict of interest br

  2019-05-09

  

  Conflict of interest Introduction Cholangiocytes Cholangiocytes are epithelial alcohol dehydrogenase inhibitor lining the intra and extrahepatic ducts of the three-dimensional network of the biliary tree. Biliary cells comprise approximately 3–5% of cells in the liver and are considered as

• Unfortunately no trends in retention in care were presented

  2019-05-09

  

  Unfortunately, no trends in retention in care were presented by Nsanzimana and colleagues, and the method used to estimate life expectancy—the abridged life table method—is not well suited to answering questions about trends in quality of care, because it info allows little scope for multivariate a

• Qu dicen las fechas en que se

  2019-05-09

  

  ¿Qué dicen las fechas en que se ha flexibilizado la posición de ambas partes? Veamos una cita elocuente sobre la situación internacional en la década de los años setenta del siglo pasado, marco en el que se mejoraron las relaciones entre Washington y La Habana, bajo el gobierno de James Carter. Por

• Two other groups subsequently published further data on

  2019-05-09

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant

• br Discussion The implant of a CRT device in a

  2019-05-09

  

  Discussion The implant of a CRT device in a patient with a resting ejection fraction of 50% represents off-guideline use of this therapy [1]. However, since the patient׳s significant NYHA Class III symptoms, LBBB and exertional ventricular dysfunction achieved evidence-based levels for improvemen

• Bone marrow resident Macs Osteomacs are located in canopy

  2019-05-09

  

  Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow gap junctions and they

• Countdown to concluded its tasks after the launch

  2019-05-08

  

  Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he

• br Martyn Plummer and colleagues September analyse the globa

  2019-05-08

  

  Martyn Plummer and colleagues (September, 2016) analyse the global burden of cancers attributable to infections in 2012. Despite the relatively low attributable proportion compared with other infectious agents, liver flukes, including and , were estimated to have caused 1300 new cases of cholangi

• Introduction Personalized medicine is the major goal of tran

  2019-05-08

  

  Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease purchase Rapalink-1 and predict clinical outcome. However, to define a specific disease p

• There are several shortcomings to

  2019-05-08

  

  There are several shortcomings to this study that need to be considered. The small size of this series is an obvious shortcoming. Due to the relative rarity of the disease, this problem is not unique to this series and authors of a recent meta-analysis noted the small sample size of other studies as

• Intravenous injection of B F melanoma cells

  2019-05-08

  

  Intravenous injection of B16F10 melanoma cells in Nf-E2-/-mice produces markedly less lung metastatic lesions compared to that in wildtype mice [5]. This provides one of the strongest confirmations for the role of platelets in hematological dissemination of tumor cells although bone tissues were not

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