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br Introduction Bone marrow fibrosis is known to occur
2019-05-13
Introduction Bone marrow fibrosis is known to occur in several neoplastic and non-neoplastic conditions. Among neoplastic conditions such as acute leukemia, it is most often seen with acute megakaryoblastic leukemia [1]. Acute promyelocytic leukemia (APL) presenting with marrow fibrosis is a rare
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br Indigenous communities experience some of the highest rat
2019-05-13
Indigenous communities experience some of the highest rates of suicide globally, especially among young people. This worrying epidemic has already been shown in Inuit communities of North America and Greenland and the Amazonian groups of Guyana, but recently has been shown to extend to Australian
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Notwithstanding issues of equity improvement of research cap
2019-05-13
Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o
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br Methods br Results A total of cases
2019-05-13
Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer
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order Boc-Pro-OH br The L type calcium channel LTCC in heart
2019-05-13
The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot
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simvastin Cisplatin based chemotherapy is commonly
2019-05-10
Cisplatin-based chemotherapy is commonly used in adjuvant CCRT, but data on carboplatin-based chemotherapy with radiotherapy is lacking. Khoury et al reported that patients treated with carboplatin-based chemoradiotherapy show worse outcomes. However, the impact on patient comorbidities was not repo
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Only of ICD implantations are performed in children
2019-05-10
Only 1% of ICD implantations are performed in children. As a result, established methods of pediatric ICD implantation are lacking, and long-term outcomes are still unclear. Non-transvenous ICD systems are required in children [1,2], and we chose an epicardial system for our case. The advantage of t
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br Una pol mica entre
2019-05-10
Una polémica entre traductores Probablemente, mientras traducía China en armas, Owen leyó y reseñó la traducción de El diablo en el cuerpo de Raymond Radiguet, hecha por Ángel Samblancat. Aun cuando aquél se dedica retinoic acid receptor perorar sobre la vida y la obra de Radiguet, a partir de lo
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br Acknowledgments We thank all the ultramarathon
2019-05-10
Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei
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Findings Three factors were significant
2019-05-10
Findings Three factors were significant predictors of treatment failure: the presence of at least 1 month of fair or poor adherence (OR 15·7, 95% CI 1·8–136·7; p=0·01); previous treatment at another clinic before the WWO/AHF Family Health Clinic (1·4, 1·2–13·7; p=0·02); and tuberculosis symptoms at
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HF is associated with the down regulation of
2019-05-10
HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th
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br Case report The patient then achieved disease
2019-05-09
Case report The patient then achieved disease-free status as noted in a series of routine image studies during regular follow-up at our oncology clinic. In November 2011, she presented due to hematuria for several days. Diagnostic cystoscopy showed a mass lesion on the urinary bladder. Whole body
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Because of high suspicion of
2019-05-09
Because of high suspicion of malignancy, we chose endoscopic ultrasound (EUS) instead of MRI of the pancreas to detect the organic lesion that caused the distal CBD stricture because initial abdominal CT did not show any suspicious lesion in the pancreas. In addition, tissue sample could be obtained
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The following is the Supplementary material related to this
2019-05-09
The following is the Supplementary material related to this article Video 1, Video 2, Video 3. Discussion In the electrophysiology setting, increased pericardial effusion or tamponade risk is associated with left-sided arrhythmia ablations, biventricular pacemaker placements, and implantable car
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br Conflict of interest br
2019-05-09
Conflict of interest Introduction Cholangiocytes Cholangiocytes are epithelial alcohol dehydrogenase inhibitor lining the intra and extrahepatic ducts of the three-dimensional network of the biliary tree. Biliary cells comprise approximately 3–5% of cells in the liver and are considered as
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