• In this study there is a limitation in

  2022-08-11

  

  In this study, there is a limitation in the study of sex differences. Only female rats were used in our study. This is because the rats cannot urinate autonomously after SCI. Manual Swainsonine emptying was needed until reflex bladder emptying was established (Lu et al., 2008, Ma et al., 2015). Beca

• br Materials and methods br Results

  2022-08-11

  

  Materials and methods Results We examined the cardiac mitochondrial density of HKI and markers of oxidative and metabolic stress in trout exposed to an aerated control exposure, an aerated (normoxic) thermal insult, or a hyperoxic thermal insult. Should mtHK provide a cardioprotective effect i

• Now recall that a cozero element of a frame

  2022-08-11

  

  Now recall that a cozero cki of a frame L is an element of the form for some continuous real-valued function h in L. Equivalently, is a cozero element if and only if there exists an such that and . This is the pointfree counterpart to the notion of a cozero set for ordinary continuous real-value

• Let Therefore where F X denotes the rate of production

  2022-08-11

  

  Let Therefore,where F(X) denotes the rate of production of new people who get infected and V(x) represents the motion of individuals in compartments, which gives us Now, the derivative of F and V calculated at an equilibrium point E0 gives matrices f and v of order 6 × 6 defined aswhere Thus, th

• The biological activity at GPR a of each of

  2022-08-11

  

  The biological activity at GPR109a of each of the 4-functionalized-5-alkyl-pyrazole-3-carboxylic acids (–) was measured using a cAMP whole cell Dynamic2 Homogenous Time-Resolved Fluorescence (HTRF) assay (). Twelve compounds were found to exhibit an EC below 1μM, and of these seven exhibited EC valu

• Flaviviruses consist of a nucleocapsid composed of multiple

  2022-08-11

  

  Flaviviruses consist of a nucleocapsid, composed of multiple copies of the capsid protein (C) and the single-stranded, positive-sense RNA genome. The nucleocapsid is surrounded by a lipid bilayer in which two transmembrane proteins are inserted, the envelope glycoprotein E and the membrane protein M

• br Materials and Methods br Results br Discussion A model

  2022-08-10

  

  Materials and Methods Results Discussion A model of seizure and excitotoxicity induced by neonatal MSG administration was described recently (19) in which extracellular glutamate increased after the first and second MSG administrations were observed, the greatest increase seen following the

• However it is unclear whether the parent and transition meta

  2022-08-10

  

  However, it is unclear whether the parent and transition metal substitution in Keggin-type phosphomolybdic NS 1738 will reveal the best effects on α-glucosidase. Therefore, the Keggin-type H3PMo12O40 (abbreviated as PMo12) and three transition metal-substituted POMs (Na4PMo11VO40, Na6PMo11FeO40 and

• CCG-1423 Expression and translocation of GLUT are regulated

  2022-08-10

  

  Expression and translocation of GLUT4 are regulated by various mechanisms including protein kinase C isoforms (PKCs) and mitogen-activated protein kinase (MAPK) signals [22], [23], but the real mechanism that statins alter expression and function of GLUT4 has not been fully identified. It is general

• In Solloway and colleagues reported

  2022-08-10

  

  In 2015, Solloway and colleagues reported that mice with alpha cell hyperplasia due to inactive hepatic glucagon receptor signaling may most likely be caused by amino x gal dependent mechanisms [11]. The authors then showed these adaptations are regulated by ‘mechanistic target of rapamycin’ (mTOR)

• Our initial lead optimization started with the

  2022-08-10

  

  Our initial lead optimization started with the modification of the indole head group as summarized in . Extensive exploration indicated that there was limited tolerance of structural change in this region of the molecule. All of the modifications to the indole moiety, including N-substitution (), li

• Ghrelin receptors in non mammals are reportedly more

  2022-08-10

  

  Ghrelin receptors in non-mammals are reportedly more “complicated/complex and diverse” than in mammals, having additional paralogs and splice variants (Kaiya et al., 2014). Several teleost fish GHS-Rs have been identified; however, functional characterization has been conducted in only a few (see, K

• Some aspects of intercellular Ca wave spread

  2022-08-10

  

  Some aspects of intercellular Ca2+ wave spread are similar to the phenomenon of spreading depression and associated with migraine headache [57]. These depolarization waves, followed by electrical inhibition, are evoked by transient hypoxia and other types of dopamine receptor antagonist injury and

• Based upon the present findings it is tempting to imagine

  2022-08-10

  

  Based upon the present findings, it is tempting to imagine that selective, and especially stable blood–brain barrier (BBB) penetrating GalR1 antagonists might be useful as drugs for acute suppression of appetite. While this may be possible, previous studies using nonspecific galanin antagonists yiel

• br Materials and methods br Results br

  2022-08-10

  

  Materials and methods Results Discussion Zn2+ is an extremely abundant transition metal in the synaptic vesicles of hippocampal glutamatergic mossy fibers and remains a key factor in the modulation of neuronal plasticity (Assaf and Chung, 1984). Disruption of Zn2+ homeostasis is associated

15084 records 335/1006 page Previous Next First page 上5页 331332333334335 下5页 Last page