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br Funding This work was supported by grants
2021-01-26
Funding This work was supported by grants to A.S. from the Swedish Cancer Foundation, Sweden (Grant number: CAN, 2015/637), the Swedish Medical Council, Sweden (Grant number: 2017- 01274), the Foundations at Skåne University Hospital, Sweden and to KB, SRS, NC, BCS, and SS from the Royal Physiogr
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On close inspection the pattern shows large areas of
2021-01-26
On close inspection, the pattern shows large areas of very low point intensity where hardly any trees can be found. Anecdotal knowledge reveals that these regions are covered by a swamp, where the tree species is known to be very unlikely to grow, independent of local soil covariates and topography.
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br Experimental protocols br Acknowledgements This research
2021-01-26
Experimental protocols Acknowledgements This research was funded by the Croatian Ministry of Science, Education and Sports (Programmes 098-0982915-2948 and 098-0982522-2525), the Austrian Science Fund FWF (DK-MCD W1226, SFB LIPOTOX F30, P22832), and the Croatian-Austrian Intergovernmental S&T
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It is common for plants
2021-01-26
It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot mdm2 inhibitor receptor ratio compared with plants in the INORG-P treatment. Additionally, greater allocat
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The indigenous populations living at high mountain regions o
2021-01-26
The indigenous populations living at high mountain regions of the Himalayas represent successful human p-nitro-Cyclic Pifithrin-α to hypoxia. These populations have undergone selective positive natural selection over millennia across several genomic loci and exhibit unique respiratory, cardiopulmon
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EZLink NHS-Biotin Kit br Protein protein interactions of LEI
2021-01-26
Protein-protein interactions of LEI/L-DNase II and the control of cell death Evolutionary tips The serpin inhibitory mechanism is extremely well adapted to evolutionary changes because a single amino EZLink NHS-Biotin Kit substitution in the RSL can led to the inhibition of a totally different
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br Results br Discussion Our UbV library was
2021-01-26
Results Discussion Our UbV library was originally designed to develop inhibitors of deubiquitinases (Ernst et al., 2013). Recently, we showed that UbVs could exhibit multiple binding modes and mechanisms to modulate HECT E3 activity (Zhang et al., 2016)—one set occupied the HECT domain E2-bind
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We initially identified four putative Egr binding
2021-01-25
We initially identified four putative Egr1 3-Deazaadenosine sale (−39/−36, −105/−102, −107/−104, and −227/−224) on the DBH proximal promoter. The deletion and mutagenesis experiments indicate that the motif at −227/−224 is required for Egr1-elicited reduction in DBH promoter activity. It remains to
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br Conclusion br Conflict of interest br
2021-01-25
Conclusion Conflict of interest Acknowledgment The authors acknowledge the grant support of the Tehran University of Medical Sciences (94-02-49-29647). Introduction Earlier in vitro observations have also established that the human 5-HT2A, while very similar to the rat isoform, exhibits
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Our data supports the conclusion that the exonuclease activi
2021-01-25
Our data supports the conclusion that the exonuclease activity thought to be intrinsic to Artemis is not a component of the Artemis polypeptide. Many possibilities exist to explain the presence of the exonuclease activity in less-pure fractions of Artemis. It is possible that the exonuclease is simp
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br Materials and methods br Results In
2021-01-25
Materials and methods Results In the leaves of the studied varieties, one to three nucleoli per nucleus were observed (Fig. 1a), except for the variety Bastardo were a maximum of two nucleoli per nucleus were detected. In the root-tip cells, most of the varieties presented one to three nucleo
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br Results On the th day the horizontal Fig and
2021-01-25
Results On the 8th day, the horizontal (Fig. 1) and vertical locomotor activity (Fig. 2) and the dorsal (Fig. 3) and Aripiprazole striatal dopamine release (Fig. 4) increased significantly in nicotine-treated rats, compared with the saline-treated rats. Tukey post-hoc test revealed the following
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Building applications by selecting and integrating component
2021-01-25
Building applications by selecting and integrating components is known in software engineering as COTS-based development. Nowadays, this approach is recognized as a crucial success factor for the software industry (Ahuja, 2014). The advantages of using COTS components include minimizing the overall
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Although the control group and tinnitus group do not
2021-01-25
Although the control group and tinnitus group do not significantly differ based on age, gender or hearing loss, a limitation of this study is that the control group is only group-matched, and not individually matched. Furthermore, we only tested hearing acuity in tinnitus patients via standard pure
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Given that dimethylamine substitution was tolerated as in SR
2021-01-25
Given that dimethylamine substitution was tolerated as in SR106447 (), we investigated Epibrassinolide synthesis amine substitutions as replacements for the -butyl group (). Cyclic amines (SR19880, 19882) or simple mono-substituted anilines (SR20037) were not active, nor was an acetylated version (
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